Gayane Hovhannisyan was born in Yerevan. She finished school N58 in Yerevan and studied at Kh. Abovyan Pedagogical Institute from 1969 to 1974. She sang in “Serpantin” ensemble. In 1972 Gayane took part in the Republican music competition "Young Voices" and won 2nd place. She won the title of laureate by participating in the Berlin International Music Festival of Young Performers in 1973. Between 1974 to 1987 she was a soloist of the State Jazz Orchestra of Konstantin Orbelian. Gayane Hovhannisyan had concerts in the US, France, Africa, Germany, Portugal and in other countries. From 1987 to 1990 worked at Lebanon and Syria, from 1994 to 1995 at Marseille. From 1996 to 2006 together with her husband she sang at Vienna circus. She returned to Yerevan in 2006 and since then teaches at State Song Theater of Armenia. In 2010 Hovhannisyan was awarded the prize in during “Tashir” Armenian music competition in Moscow, in 2011 she was awarded the title of Honored Artist of Armenia.