Hakob Vardanyan was born in Yerevan. He studied at Yerevan Komitas State Conservatory, in 1951 he participated in the III World Festival in Berlin, during which he gave 17 concerts in various cities of Germany, as well as in Poland and Albania. After finishing studies he became a soloist at Armphilharmonic. Hakob Vardanyan was a professor at Komitas State Conservatory, in 1963 he received the title Honored Artist of Armenian SSR. Died in Yerevan.